GSK-3β inhibitor 14

CAS No. 863004-48-2

GSK-3β inhibitor 14( —— )

Catalog No. M36031 CAS No. 863004-48-2

GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 134 In Stock
5MG 198 In Stock
10MG 301 In Stock
25MG 466 In Stock
50MG 624 In Stock
100MG 826 In Stock
200MG 1098 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GSK-3β inhibitor 14
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.
  • Description
    GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    GSK-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    863004-48-2
  • Formula Weight
    283.39
  • Molecular Formula
    C17H17NOS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1C=2C(SC(C)CC1=O)=CC=CC2)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103.?
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